STAT3 Antibody

Cat no: 251107

Supplier: ABBIOTEC

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Description
Additional Information

STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).

Catalogue number:	251107
Reactivities:	Human, Mouse, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P40763
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF