STAT5

Cat no: 251511

Supplier: ABBIOTEC

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Description
Additional Information

Signal transducer and activator of transcription 5A (STAT5) carries out a dual function: signal transduction and activation of transcription. STAT5 is tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone,Porcinerolactin, erythropoietin and thrombopoietin. Phosphorylation results in translocation into the nucleus, where it binds to the GAS element and activates transcription. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for ma, Xenopus/Amphibian,imal transcriptional activity.

Catalogue number:	251511
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P42229
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT5.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Signal transducer and activator of transcription 5A; STAT5A; STAT5