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Stromal cell-derived factor 1b, 22-93aa, Recombinant Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b)

Cat no: S7975-65A

Stromal cell-derived factor 1b, 22-93aa, Recombinant Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b)

SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma. \n\nSource:\nRecombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli.\n\nSequence of amino acids:\nMGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM\n\nEndotoxin Level: (same/less than)1EU/ug\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S7975-65A

Size

50ug

Form

Supplied as liquid in 20mM Tris-HCl, pH8.0, 10% glycerol.

Purity

(same/more than)90% (SDS-PAGE)

References

1. Arya M., et al. (2007). Tumour Biol. 28(3):123-31, 2. Kucia M., et al. (2005). Stem Cells. 23(7):879-94.

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