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Stromatoxin-1

Cat no: STS-350

Stromatoxin-1

Stromatoxin-1. A Potent Blocker of Kv2.1, Kv2.1/9.3, Kv2.2, and Kv4.2 channels.

Stromatoxin-1 is a 34 amino acid peptidyl toxin originally isolated from Stromatopelma calceatum tarantula. Structurally, Stromatoxin-1 belongs to the scaffold of structural inhibitor cysteine knot peptide family, which were shown to function as gating modifiers.

Stromatoxin-1 selectively inhibits Kv2.1, Kv2.1/9.3, and Kv4.2 channel currents (IC50 of 12.7 nM, 7.2 nM and 1.2 nM respectively), and is the first high-affinity voltage gating modifier inhibitor of the Kv2.2 channel subtype (IC50, 21.4 nM) to be discovered.

Alomone Labs is pleased to offer Stromatoxin-1, a synthetic product in economical sizes and at very attractive prices.

Ion Channel Modulators; K+ Channel Blockers

Prices direct from Alomone Labs Ltd.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

STS-350

Size

5 x 10 micro g

Purity

>98%

Concentration

1.2-670 nM.

Shipping Temp

Room Temperature

Molecular Weight

3788 da

SUPPLIER INFO

Alomone Labs Ltd.

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