Home  >  Products  >  Structural Maintenance of Chromosomes 4 (SMC4, SMC-4, Chromosome-associated Polypeptide C, CAPC, CAP-C, hCAP-C, Structural Maintenance of Chromosomes 4-like 1, SMC4L1, XCAP-C Homolog)
Structural Maintenance of Chromosomes 4 (SMC4, SMC-4, Chromosome-associated Polypeptide C, CAPC, CAP-C, hCAP-C, Structural Maintenance of Chromosomes 4-like 1, SMC4L1, XCAP-C Homolog)

Structural Maintenance of Chromosomes 4 (SMC4, SMC-4, Chromosome-associated Polypeptide C, CAPC, CAP-C, hCAP-C, Structural Maintenance of Chromosomes 4-like 1, SMC4L1, XCAP-C Homolog)

Cat no: S7983-01E

Supplier: United States Biological
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The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Ramos cell lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7983-01E
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Ball Jr AR and Yokomori K. Chromosome Res. 9(2): 85-96 (2001). 2. Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y. J Hum Genet. 44(3):197-202 (1999). 3. Schmiesing JA, Ball AR Jr, Gregson HC, Alderton JM, Zhou S, Yokomori K. Proc Natl Acad Sci USA. 95(22): 12906-12911 (1998).
Additional info: Recognizes human CAP-C. Species sequence homology: mouse, rat, xenopus, chicken.

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