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STX12, Recombinant, Human, aa1-248, His-Tag (Syntaxin-12, Syntaxin 12)

Cat no: 045464

STX12, Recombinant, Human, aa1-248, His-Tag (Syntaxin-12, Syntaxin 12)

Syntaxin 12, also known as, belongs to the syntaxin family. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I).\n\nSource:\nRecombinant corresponding to aa1-248 from human STX12, fused to His-tag at N-terminus, expressed in E.coli.\n\nMolecular Weight:\n~31kD (272aa) confirmed by MALDI-TOF\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSHMSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDS SKLQENLQQL QHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSE KEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADIL DVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

045464

Size

20ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.2M sodium chloride, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Tang B L., et al. (1998) J Biol Chem. 273:6944-6950. 2. Prekeris R., et al. (1998) J Cell Biol. 143: 957-971.

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