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Sulochrin

Cat no: S8025-40


Supplier: United States Biological
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Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp.. An anti-angiogenic agent it inhibits vascular endothelial growth factor (VEGF) leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also inhibits eosinophil activation and chemotaxis. Purity: >99% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Catalogue number: S8025-40
Size: 1mg
Purity: >99% by HPLC
References: 1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552. 2. Effects of ortho-substituent groups of sulochrin on inhibitory activity to eosinophil degranulation. Ohashi H. et al. Bioorg. Med. Chem. Lett. 1999, 9, 1945. 3. Sulochrin inhibits eosinophil activation and chemotaxis. Ohashi H. et al. Inflamm. Res. 1998, 47, 409.

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