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Sumanirole Maleate

Cat no: 021205


Supplier: United States Biological
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Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits anti-Parkinsonian activity similar to Ropinirole. Form: Off-White to Light Beige Solid Melting Point: 206-208 degrees C (dec.) Solubility: DMSO, Methanol Pfizer Compound
Catalogue number: 021205
Size: 10mg
Form: Off-White to Light Beige Solid
Alternative names: (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate; (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin- 2(1H)-one (2Z)-2-Butenedioate;
References: McCall, et al.: J. Pharmacol. Exp. Ther., 314 1248 (2005), Stephenson, et al.: J. Pharmacol. Exp. Ther., 314 1257 (2005),

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