Superoxide Dismutase, Cu,Zn (SOD1)

Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel.\n\nApplications:\nSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilutions:\nImmunohistochemistry (Paraffin): Does not require pre-treatment (trypsin or pronase) prior to staining or antigen retrieval using heat treatment methods prior to staining of paraffin sections.\nImmunohistochemistry: Frozen sections\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHuman spleen and lymph node.\n\nHybridoma:\nSp-2/0-Ag14 myeloma cell line with spleen cells from immunized mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S8060-14E

Size

100ug

Applications

ELISA, IHC

Hosts

Mouse

Reactivities

Hum, Mouse, Bov

Form

Supplied as a liquid in PBS, 0.1% BSA, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes bovine Superoxide Dismutase, Cu, Zn. Does not cross react with immunoglobulins but does react weakly with Mn SOD. Species Crossreactivity: human and mouse