Surfactant protein A (6F10) Antibody

Cat no: 250400

Supplier: ABBIOTEC

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Description
Additional Information

Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance o, Xenopus/Amphibian,ygen radical production by alveolar macrophages. The serum concentration is 45 ng/ml in healthy individuals. This antibody is specific for human pulmonary SP-A.

Catalogue number:	250400
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.2 mg
Accession:	Q8IWL2
Antigen:	Native SP-A purified from bronchioaveolar lavage from proteinosis patients
Format:	Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1/k
Clonality:	6F10
Additional info:	Pulmonary surfactant-associated protein A1; SP-A1; SP-A; PSP-A; PSPA; Alveolar proteinosis protein; 35 kDa pulmonary surfactant-associated protein