Surfactant protein D (10B2) Antibody

Cat no: 250403

Supplier: ABBIOTEC

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Description
Additional Information

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance o, Xenopus/Amphibian,ygen radical production by alveolar macrophages. The serum concentration is appro, Xenopus/Amphibian,imately 700 ng/ml in healthy individuals. This antibody is specific for SP-D from amniotic fluid, serum and bronchioalveolar lavage. The antibody blocks SP-D binding to GP-340 but not to carbohydrates.

Catalogue number:	250403
Reactivities:	Human
Applications:	Western Blot
Size:	0.2 mg
Accession:	P35247
Antigen:	Native human SP-D purified from late pregnancy amniotic fluid
Format:	Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a/k
Clonality:	10B2
Additional info:	Pulmonary surfactant-associated protein D; SP-D; PSP-D; PSPD; Lung surfactant protein D