sVEGFR1/sFLT1 BioAssay(TM) ELISA Kit, Human

Sandwich ELISA quantitative detection kit for Human sVEGFR1/sFLT1 in cell culture supernates, serum and plasma (EDTA).\n\nsVEGFR1, also known as sFMS-related tyrosine kinase 1(sFLT1). Oncogene sFLT belongs to the src gene family and is related to oncogene ROS . Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. sFLT is mapped to 13q12. sVEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. The standard product used in this kit is recombinant human sVEGFR1, consisting of 905 amino acids with the molecular mass of 100kD.\n\nAssay Range:\n156pg/ml-10, 000pg/ml\n\nSensitivity:\n< 30 pg/ml\n\nCrossreactivity:\nThere is no detectable cross-reactivity with other relevant proteins.\n\nUniprot ID:\nP17948\n\nEntrez Gene ID:\n2321\n\nKit Components:\n96-well plate pre-coated with anti-sVEGFR1/sFLT1, Human\nLyophilized recombinant sVEGFR1/sFLT1, Human standard, 10ng/tube, 2Ea\nUSB Cat No Kit Component\n143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)\n143697 Sample diluent buffer, 30ml\n143698 Antibody diluent buffer, 12ml\n143699 ABC diluent buffer, 12ml\n143700 TMB color developing agent, 10ml\n143701 TMB stop solution, 10ml\n\nStorage and Handling:\nStore at 4 degrees C for 6 months, at -20 degrees C for 12 months. Avoid multiple freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

144047

Size

96Tests

References

1. Imbert, A.; Rosnet, O.; Marchetto, S.; Ollendorff, V.; Birnbaum, D.; Pebusque, M.-J. : Characterization of a yeast artificial chromosome from human chromosome band 13q12 containing the FLT1 and FLT3 receptor-type tyrosine kinase genes. Cytogenet. Cell Genet. 67: 175-177, 1994.\n2. Niida, S.; Kondo, T.; Hiratsuka, S.; Hayashi, S.-I.; Amizuka, N.; Noda, T.; Ikeda, K.; Shibuya, M. : VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc. Nat. Acad. Sci. 102: 14016-14021, 2005.\n