Synapsin I

Cat no: S9104-01E

Supplier: United States Biological

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The synapsins are a family of proteins that have long been implicated in the regulation of neurotransmitter release at synapses. Specifically, they are thought to be involved in regulating the number of synaptic vesicles available for release via Exocytosis. All synapsins contain a short amino-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I. Phosphorylation of synapsin amino-terminal domain at serine 9 inhibits its binding tophospholipids and dissociates synapsins from synaptic vesicles. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry: 1:50 (Frozen Sections) Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	S9104-01E
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	100ul
Form:	Supplied as a liquid in PBS, 10mM sodium HEPES, pH7.5, 150mM sodium chlordie, 100ug BSA and 50% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Detects endogenous levels of total synapsin protein. Expected to recognize all synapsin isoforms. Reacts with residues 430-443 [DYNGNLHEALQRIT] of the NC3 region of human and mouse CLAC-P.

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Synapsin I

Cat no: S9104-01E

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