Synoretin (A111) pAb

The synucleins, including (alpha)-synuclein (also designated NACP for nonamyloid component precursor), (beta)-synuclein (also designated PNP 14 for phosphoneuroprotein 14), and (gamma)-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. (alpha)-Synuclein, identified as a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of (alpha)-synuclein and (beta)-synuclein may be important during hematopoetic cell differentiation. A mutant form of (alpha)-synuclein is found in patients with early onset Parkinson's disease. (gamma)-Synuclein is associated with axonal pathology in Parkinson's disease.

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SPECIFICATIONS

Catalog Number

BS1429

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 81-130 of Human Synoretin.

Species

Synuclein (gamma) (A111) pAb detects endogenous levels of Synuclein (gamma) protein.

Dilutions

WB: 1:500~1:1000\nIHC: 1:50~1:200

Swiss Prot

O76070

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 20 kDa

Alternative Names

Gamma-synuclein; (gamma)-synuclein; Synuclein (gamma); Synuclein-(gamma); Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR; SNCG; BCSG1; PERSYN; PRSN