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Synphilin-1 (R846) pAb

Synphilin-1 (R846) pAb

Cat no: BS2939

Supplier: Bioworld Technology, Inc.
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Synphilin-1 ((alpha)-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with (alpha) synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including (alpha)-synuclein and (beta)-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both (alpha)-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson's disease, only mutations in the gene for (alpha)-synuclein have been determined to confer pathogenicity.
Catalogue number: BS2939
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q9Y6H5
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 815-867 of Human Synphilin-1.
Species: Synphilin-1 (R846) pAb detects endogenous levels of Synphilin-1 protein.
Molecular weight: ~ 100 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Synphilin-1; Sph1; Alpha-synuclein-interacting protein; SNCAIP
Additional info: For research use only, not for use in diagnostic procedure.

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