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Syntaxin 1A (Synaptotagmin-Associated 35kD Protein, Neuron-Specific Antigen HPC-1)

Cat no: S9205-03D

Syntaxin 1A (Synaptotagmin-Associated 35kD Protein, Neuron-Specific Antigen HPC-1)

Syntaxin 1A, 1-226aa, human, recombinant, E. coli\nSynonyms: Neuron-specific antigen HPC-1, STX 1, syntaxin brain, p35-1 \n\nSyntaxin is membrane integrated Q-SNARE protein participating in exocytosis. Syntaxin is composed of an N-terminal regulatory domain (Habc), a SNARE domain (known as H3), and a single C-terminal transmembrane domain. The SNARE(H3) domain binds to both synaptobrevin and SNAP-25 forming the core SNARE complex. Recombinant syntaxin 1A protein (1-226aa) contains N-terminal domain(Habc) and t_SNARE domain(H3 domain) and this protein was overexpressed in E.coli and purified by using the conventional column chromatography techniques.\n \nMolecular Weight: 26.1kD (226 aa)\n\nSequences:\nMKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA \nILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH\nSTLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG\nIIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQ\n\nStorage: Store at -20 degrees C. Avoid freeze/thaw cycles\n \n\n

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SPECIFICATIONS

Catalog Number

S9205-03D

Size

100ug

Form

Supplied as a liquid in 20mM Tris, pH 7.5, 1mM DTT, 10% glycerol.

Purity

(same/more than) 95% by SDS PAGE

References

Han X, Wang CT, Bai J, Chapman ER, Jackson MB (2004). Science 304: 289-292\nWoodbury DJ, Rognlien K. (2000). Cell Biology International 24(11): 809-818

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