Beta synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heatresistant. Beta synucelin also has a chaperone-like activity. Recently, beta synuclein has been suggested to inhibit alpha synuclein aggregation.
Molecular Weight:
14,287 (Molecular size on SDS-PAGE will be shift up)
Sequence:
MDVFMKGLSM/ AKEGVVAAAE/ KTKQGVTEAA/ EKTKEGVLYV/ GSKTREGVVQ/ GVASVAEKTK/ EQASHLGGAV/ FSGAGNIAAA/ TGLVKREEFP/ TDLKPEEVAQ/ EAAEEPLIEP/ LMEPEGESYE/ DPPQEEYQEY/ EPEA
Storage and Stability:
May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.