SYVN1 Antibody

Cat no: 200108

Supplier: ABBIOTEC

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Description
Additional Information

Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-e, Xenopus/Amphibian,panded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis.

Catalogue number:	200108
Reactivities:	Human, Mouse, Rabbit
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q86TM6, NP_115807
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SYVN1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	E3 ubiquitin-protein ligase synoviolin; Synovial apoptosis inhibitor 1; HRD1; SYVN1