TAB2 (3B5) Antibody

Cat no: 253082

Supplier: ABBIOTEC

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Description
Additional Information

TAB2 (TGF-beta-activated kinase 1 and MAP3K7-binding protein 2) is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase comple, Xenopus/Amphibian, with TRAF6,Mouse,AP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2 with TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Catalogue number:	253082
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	Q9NYJ8
Antigen:	Purified recombinant fragment of human TAB2 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3B5
Additional info:	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2; KIAA0733; MAP3K7IP2; TAB2