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TAF5L (E323) Peptide

Cat no: BS2460P

TAF5L (E323) Peptide

TFIID is a general transcription factor that initiates preinitiation complex as-sembly through direct interaction with the TATA promoter element. Functioning as a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs), TFIID mediates promoter responses to various transcriptional activators and repressors. TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes.

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SPECIFICATIONS

Catalog Number

BS2460P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TAF5L (E323). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O75529

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2460 TAF5L (E323) pAb.

Alternative Names

TAF 5L; PAF65 beta; PAF65B; PCAF associated factor 65 Taf5l; Taf5l protein;

SUPPLIER INFO

Bioworld Technology, Inc.

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