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TAF6 (Transcription Initiation Factor TFIID Subunit 6, Transcription Initiation Factor TFIID 70kD Subunit, TAF(II)70, TAFII-70, TAFII70, Transcription Initiation Factor TFIID 80kD Subunit, TAF(II)80, TAFII-80, TAFII80, p80, Taf2e)

Cat no: 029619

TAF6 (Transcription Initiation Factor TFIID Subunit 6, Transcription Initiation Factor TFIID 70kD Subunit, TAF(II)70, TAFII-70, TAFII70, Transcription Initiation Factor TFIID 80kD Subunit, TAF(II)80, TAFII-80, TAFII80, p80, Taf2e)

Fourteen TBP-associated factors (TAFs) and the TATA-binding protein (TBP) form the TFIID complex, which is used to recognize core promoters. TAF6 is known to have a histone fold domain (HFD) and is associated with histone H4. TAF6 is pivotal to the transcription of the p53 tumor suppressor protein and a splice variant of TAF6, TAF6delta, has been found to be essential for apoptosis signaling without p53.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.1ug/ml\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nMouse embryonic stem cell lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

029619

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Mouse

Form

Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Wilhelm, E., et al. (2010). BMC Mol Biol. 11:10. 2. Wilhelm, E., et al. (2008). PLoS One. 3(7): e2721. 3. Shao, H., et al. (2005). Mol Cell Biol. 25(1): 206-219

Additional Info

Recognizes mouseTAF6. Species sequence homology: Rat (100%), human (99%).

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