Supplier:
Alomone Labs Ltd.Cat no: T-460
Taipoxin
Intoxicated animals die of asphyxia caused by a complete inhibition of neurotransmitter release and neuromuscular junction blockage of the respiratory muscles. In the central nervous system taipoxin blocks synaptic vesicle recycling by inhibiting the neuronal uptake pathway through the interaction with neuronal Pentraxin system components during synapse formation and remodeling.
In neuronal cultures, Taipoxin facilitates Ca2+ -dependent synaptic vesicle exocytosis and causes a complete depletion of stored neurotransmitter, resulting in synaptic transmission blockage. Taipoxin, at nanomolar range, causes swelling of nerve terminus and redistributon of synaptic vesicle proteins.
Alomone Labs is pleased to offerTaipoxin (#T-460), a natural native toxin purified to homogeneity from the Australian taipan Oxyuranus s. scutellatus.
Neurotoxins> Inhibitory Neurotoxins.
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SPECIFICATIONS
Catalog Number
T-460
Size
5 x 0.5 mg
Purity
>97%
Concentration
10-50 nM
Shipping Temp
Room Temperature
Molecular Weight
46 kDa
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