TANK, NT (TRAF Family Member-associated NF-kappa-B Activator, TRAF-interacting Protein, I-TRAF, ITRAF, TRAF2)

Cat no: T8171-75D

Supplier: United States Biological

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Description
Additional Information

Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	T8171-75D
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in PBS, 0.02% sodium azide.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes human TANK.

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TANK, NT (TRAF Family Member-associated NF-kappa-B Activator, TRAF-interacting Protein, I-TRAF, ITRAF, TRAF2)

Cat no: T8171-75D

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