It is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis.
Form:
Off-White to Pale Yellow Solid
Melting Point:
>300 degrees C (dec.)
Solubility:
Chloroform
Method for Determining Identity: Proton NMR (CDCl3) and MS
TLC Conditions: SiO2; Dichloromethane: Methanol: Ammonium Hydroxide (8:2:0.1); Visualized with UV and KMnO4; Rf= 0.50
Perdue, G.P., et al.: J. Pharm. Sci., 68, 124 (1979), Tsacheva, I., et al.: J. Biosci., 59, 528 (2004), Zhang, Y., et al.: Cancer Lett., 262 103 (2008),
Quick Search
