Tau (Tau Protein, Microtubule-associated Protein Tau, MAPT, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1)

Supplier:

United States Biological

Cat no: T1030-01A

Tau (Tau Protein, Microtubule-associated Protein Tau, MAPT, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1)

The microtubule-associated proteins (MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441aa. The isoforms differ from each other by the presence or absence of 29-aa or 58-aa inserts located in the N terminus and a 31-amino repeat located in the C terminus. Tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau (MTBT1) is mapped to chromosome 17q21.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-1ug/ml\nImmunohistochemistry (paraffin): 1-2ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 1.2% sodium acetate . Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T1030-01A

Size

100ug

Applications

IHC, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov

Form

Supplied as a lyophilized powder from 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute with 1.2% sodium acetate, PBS.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Additional Info

Recognizes Tau. Species Crossreactivity: human, mouse, rat.

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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Reactivities

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