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TAX1BP3, Recombinant, Human, aa1-124, His-tag (Tax1-binding Protein 3, Glutaminase-interacting Protein 3, Tax Interaction Protein 1, TIP-1, TIP1)

TAX1BP3, Recombinant, Human, aa1-124, His-tag (Tax1-binding Protein 3, Glutaminase-interacting Protein 3, Tax Interaction Protein 1, TIP-1, TIP1)

Cat no: 029705

Supplier: United States Biological
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TAX1BP3, contains one PDZ domain, through which most of its interactions with other proteins are made. The PDZ domain of TAX1BP3 interacts with the C-terminus of Rhotekin to facilitate Rho-mediated activation of the FOS serum response element. The PDZ domain also interacts with beta-catenin to inhibit the transcriptional activity of beta-catenin. It has been detected in a variety of cell lines, including HeLa, and is weakly expressed in peripheral blood leukocytes Source: Recombinant corresponding to aa1-124 from human TAX1BP3, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSYIPGQPVT AVVQRVEIHK LRQGENLILG FSIGGGIDQD PSQNPFSEDK TDKGIYVTRV SEGGPAEIAG LQIGDKIMQV NGWDMTMVTH DQARKRLTKR SEEVVRLLVT RQSLQKAVQQ SML Molecular Weight: ~15.8kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029705
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 20% glycerol, 0.1M sodium chloride, 1mM DTT.
Purity: ~95% (SDS-PAGE)
References: 1. Rousset R. et al. (1998) Oncogene.16: 643-654 2. Reynaud C. et al. (2000) 3. J. Biol. Chem. 275: 33962-33968.

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