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TBCA (Tubulin folding cofactor A)

TBCA (Tubulin folding cofactor A)

Cat no: T9157-32

Supplier: United States Biological
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Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: T9157-32
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ul
Form: Supplied as a Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
P type: Mab
Isotype: IgG2b
Purity: Purified by immunoaffinity chromatography.
References: 1.HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Nolasco%20S%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus" Nolasco S, et al., (2005) HYPERLINK "javascript:AL_get(this,%20'jour',%20'FEBS%20Lett.');" FEBS Lett 579(17):3515-3524 2. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tian%20G%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus" Tian G, et al., (1996) Cell 86(2):287-296
Additional info: Recognizes human TBCA

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