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TBX4, NT (TBX4, T-box transcription factor TBX4)

Cat no: 042669

TBX4, NT (TBX4, T-box transcription factor TBX4)

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

042669

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)\nJugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :\nZhao, J., et al. BMC Med. Genet. 11, 96 (2010) :\nYerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)\nGudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)

Additional Info

Human

Alternative Names

TBX4, T-box transcription factor TBX4

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