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TCF3 (Transcription factor 3, Transcription factor E2-alpha, Immunoglobulin transcription factor 1, ITF1)

Cat no: 030679

TCF3 (Transcription factor 3, Transcription factor E2-alpha, Immunoglobulin transcription factor 1, ITF1)

Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.\n\nApplications:\nWestern Bloting: 1:500-1:2000.\nFlow cytometry: 1:200-1:400.\nELISA: Suggested dilution 1:10000.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

030679

Size

100ul

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

Form

Ascites fluid, 0.03% sodium azide.

P Type

Mab

Purity

Ascites

Isotype

IgG1

References

1.J Biol Chem. 2000 Oct 27;275(43):33567-73.\n2.Mol Cell Biol. 2001 Mar;21(5):1866-73.\n3.J Biol Chem. 2003 Jan 24;278(4):2370-6. Epub 2002 Nov 14.

Additional Info

Human

Alternative Names

E2A; ITF1; VDIR; bHLHb21; MGC129647; MGC129648; TCF3

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