TCL1A (T-cell Leukemia/Lymphoma Protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1)

Cat no: T2017-10E

Supplier: United States Biological

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Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml, observed in lysates of cell lines daudi and Jurkat on ~16kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	T2017-10E
Reactivities:	Human
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Shen RR, Ferguson DO, Renard M, Hoyer KK, Kim U, Hao X, Alt FW, Roeder RG, Morse HC 3rd, Teitell MA. Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation. Blood. 2006 Sep 15;108(6):1991-8. Epub 2006 May 25.
Additional info:	Recognizes human TCL1A.

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TCL1A (T-cell Leukemia/Lymphoma Protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1)

Cat no: T2017-10E

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