TCP-1(zeta)pAb

Cat no: BS5959

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 (alpha), (beta), (gamma), (delta), E, ?, n and 0, each encoded by a different gene. Two (zeta)subunits have been described: TCP-1 (zeta)(also designated TCP-1 ?1) and TCP-1 ?2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Catalogue number:	BS5959
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P40227
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 216-261 of Human TCP-1?.
Species:	TCP-1(zeta)pAb detects endogenous levels of TCP-1(zeta)protein.
Molecular weight:	~ 60 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	T-complex protein 1 subunit zeta; TCP-1-zeta; Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20; CCT6A; CCT6; CCTZ; TCP1?; TCP 1?; TCP1-?; TCP-1-?; CCT-?-1; CCT?-1; CCT-?1; CCT?1;
Additional info:	For research use only, not for use in diagnostic procedure.

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TCP-1(zeta)pAb

Cat no: BS5959

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