TDP43 Antibody

Cat no: 253225

Supplier: ABBIOTEC

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Description
Additional Information

TAR DNA-binding protein 43 (TDP-43) is a DNA and RNA-binding protein which regulates transcription and splicing. TDP-43 is involved in the regulation of CFTR splicing, and promotes CFTR e, Xenopus/Amphibian,on 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this e, Xenopus/Amphibian,on. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TDP-43 is also involved in microRNA biogenesis, apoptosis, and cell division. TDP-43 can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Catalogue number:	253225
Reactivities:	Human, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q13148
Antigen:	KLH-conjugated peptide encompassing a sequence within the C-term region of human TDP43.
Format:	Each vial contains 0.1 ml IgG in PBS pH7.4, 30% glycerol with 0.065% sodium azide. Antibody was purified byimmunogen affinity precipitation.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	TDP-43; TARDBP; TAR DNA-binding protein 43; TDP43