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TEF (K224) Peptide

Cat no: BS2041P

TEF (K224) Peptide

TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSHbeta promoter. While broadly expressed in adults, TEF is only found in developing embryonic anterior pituitary gland. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by downregulating beta chain expression of cytokine receptors. The functional domains of TEF are highly homologous with other members of the PAR-bZIP subfamily, including albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP). The gene encoding TEF maps to human chromosome 22q13.2.

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SPECIFICATIONS

Catalog Number

BS2041P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TEF (K224). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q10587

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2041 TEF (K224) pAb.

Alternative Names

Tef; TEF; tefa; tefb; tefbeta; thyrotroph embryonic factor; VBP;

SUPPLIER INFO

Bioworld Technology, Inc.

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