Teicoplanin Complex (Teichomycin, Tecoplanin, Targocid, Teicomid, Antibiotic 8327A, DL 507IT, L12507, MDL 507, MW 1900)

Teicoplanin complex is family of closely related metabolites produced by Actinoplanes teichomyceticus which possesses potent broad spectrum antibiotic activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. The metabolites share a common glycopeptide core (teicoplanin A3) on which a family of fatty acids varying in length, degree of saturation and branching are linked as amides through one of the aminoglycoside moieties. The major component of the complex is teicoplanin A2 which comprises five major components (teicoplanin A2-1 to A2-5), teicoplanin A3 and four minor components (named teicoplanin RS-1 to RS-4).\n\nSource:\nTeicoplanin Complex \n\nMolecular Weight:\n~1879.7\n\nSolubility:\nSoluble in H2O.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with H2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

T2223

Size

25mg

Form

Supplied as a white solid.

Purity

(same/more than) 95% by HPLC

References

1. Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. Parenti, F., et al., J. Antibiotics 31: 276 (1978). 2. Teicoplanin. Goldstein B. P. et al. In: Glycopeptide antibiotics edited by Nagarajan R. Dekker New York, 273 (1994).

Alternative Names

Teichomycin, Tecoplanin, Targocid, Teicomid, Antibiotic 8327A, DL 507IT, L12507, MDL 507, MW 1900