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Tenofovir Disoproxil Fumarate

Cat no: 021351


Supplier: United States Biological
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Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. Melting Point: 113-116 degrees C Solubility: DMSO, Methanol Method for Determining Identity: Proton NMR (DMSO-d6) and MS TLC Conditions: C18; Methanol : Water (1:1). Visualized with UV and KMnO4 (Rf= 0.30). Storage and Stability: Store at 4 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Catalogue number: 021351
Size: 10mg
Form: White solid
Purity: ~95%. Contains 1% DCM and ~1% ethyl acetate.
Alternative names: 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid 1,9-Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate; GS 4331-05; PMPA Prodrug
References: Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),

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