Home  >  Products  >  TERF1 (Telomeric Repeat-binding Factor 1, NIMA-interacting Protein 2, TTAGGG Repeat-binding Factor 1, Telomeric Protein Pin2/TRF1, PIN2, TRBF1, TRF, TRF1)

TERF1 (Telomeric Repeat-binding Factor 1, NIMA-interacting Protein 2, TTAGGG Repeat-binding Factor 1, Telomeric Protein Pin2/TRF1, PIN2, TRBF1, TRF, TRF1)

Cat no: T2395-04G


Supplier: United States Biological
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TERF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 1-3ug/ml, HeLa lysate observed on ~60-65kD and 45kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T2395-04G
Reactivities: Human, Bovine, Porcine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T. A human telomeric protein. Science. 1995 Dec 8;270(5242):1663-7.
Additional info: Recognizes human TERF1. Species sequence homology: porcine and bovine.

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