Testosterone, Human, BioAssay(TM) ELISA Kit

Supplier:

United States Biological

Cat no: T2949-01H

Testosterone, Human, BioAssay(TM) ELISA Kit

Sample Type:\nSerum\n\nIntended Use:\nFor the quantitative determination of Testosterone concentration in human serum\n\nIntroduction:\nTestosterone (17B-hydroxyandrost-4-ene-3-one) is a C19 steroid with an unsaturated bond between C-4 and C-5, a ketone group in C-3 and a hydroxyl group in the B position at C-17. This steroid hormone has a molecular weight of 288.4. Testosterone is the most important androgen secreted into the blood. In males, testosterone is secreted primarily by the Leydig cells of the testes; in females ca. 50% of circulating testosterone is derived from peripheral conversion of androstenedione, ca. 25% from the ovary and ca. 25% from the adrenal glands.\nTestosterone is responsible for the development of secondary male sex characteristics and its measurements are helpful in evaluating the hypogonadal states. In women, high levels of testosterone are generally found in hirsutism and virilization, polycystic ovaries, ovarian tumors, adrenal tumors and adrenal hyperplasia. In men, high levels of testosterone are associated with hypothalamic pituitary unit diseases, testicular tumors, congenital adrenal hyperplasia and prostate cancer. Low levels of testosterone can be found in patients with the following diseases: Hypopituitarism, Klinefelter

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SPECIFICATIONS

Catalog Number

T2949-01H

Size

1Kit

References

1. Chen, A., Bookstein, J.J., Meldrum, D.R., Diagnosis of a testosterone-secreting adrenal adenoma by selective venous catheterization. Fertil. Steril., 1991; 55: 1202-1203. 2. Granoff, A.B. and Abraham, G.E., Peripheral and adrenal venous levels of steroids in a patient with virilizing adrenal adenoma. Obstet. Gynecol., 1979; 53:111-115. 3. Bricaire, C., Raynaud, A., Benotmane, A., et al., Selective venous catheterization in the evaluation of hyperandrogenism. J. Endocrinol Invest., 1991; 14: 949-956.\n4. Heinonen, P.K., Androgen production by epithelial ovarian tumours in post-menopausal women. Maturitas, 1991; 13: 117- 117-122. 5. Tietz, N.W. ed., Clinical Guide to Laboratory Tests, 3rd Edition,\nW.B. Saunders, Co., Philadelphia, 1995: 578-580. 6. USA Center for Disease Control/National Institute of Health Manual,

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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