Tetracycline Hydrochloride

Tetracycline is an antibiotic which has the ability to inhibit the growth of wide variety of organisms, including gram-positive and gram-negative bacteria, rickettsias, mycoplasmas, chlamydias, and certain viruses, protozoa, and actinomycetes. It interferes with the production of proteins that the bacteria need to multiply and divide (bacteriostatic). Tetracycline Hydrochloride mode of action is as a protein synthesis inhibitor via an aminoacyl-tRNA binding mechanism to the 30S subunit. Mode of resistance is the loss of cell wall permeability. \n\nApplications: Recommended for use in cell culture applications.\n\nRecommended Dilutions:\nCell Culture: 10mg/L. Stable at 37 degrees C for 4 days.\n\nSolubility: Water soluble at 5-10g/100ml\nConforms to the following USP28 References:\nAppearance: Yellow crystalline powder\nPurity: 95-105%\nPotency (Assay): (same/more than) 900ug/mg\nIdentification A (IR): Conforms\nIdentification B (UV): Conforms\nIdentification C (HPLC): Conforms\nCrystallinity: Conforms\nLoss on Drying: (same/less than) 2.0%\nHeavy Metals: (same/less than) 0.005%\n4-Epianhydrotetracycline: (same/less than) 2%\nAnhydrotetracycline: (same/less than) 0.5%\npH (10mg/ml): 1.8-2.8\nSpecific Optical Rotation: -240-255 degrees \nIndividual Related Substance: (same/less than) 3%\nTotal Unknown Related Substance: (same/less than) 5%\nBulk Density: 0.42-0.55g/ml\nResidual Solvent: \nacetone: (same/less than) 0.02%\nn-butanol: (same/less than) 0.2%\n\nTallow derivatives: Produced on the basis of chemical synthetic process; no any animal material contained during the whole production process and also no raw materials are used which are generated from animals during production.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile dH2O. Filter sterilize, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts