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Products tetranor-PGDM EIA Kit
| Catalogue number: | 501001 |
| Weight: | 0 |
| Form: | 96 Well |
| P type: | Prostaglandins|Assay Kits|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | tetranor-PGDM is a major metabolite of prostaglandin D2 (PGD2) found in human and mouse urine. In human urine, tetranor-PGDM is significantly more abundant than the PGD2 metabolites 11(beta)-PGF2(alpha) and 2,3-dinor-11(beta)-PGF2(alpha) and is the only endogenous PGD2 metabolite detectable in mouse urine by LC-MS. Normal levels of tetranor-PGDM in human and mouse urine are 1.5 ng/mg creatinine and 8.1 ng/mg creatinine respectively. Cayman's tetranor-PGDM EIA Kit is a competitive assay that can be used for quantification of tetranor-PGDM in urine. This assay converts tetranor-PGDM to a stable derivative, tetranor-PGJM, that can be easily quantified. The EIA typically displays an IC50 (50% B/B0) of approximately 170 pg/ml and a detection limit (80% B/B0) of approximately 40 pg/ml. |
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