Home  >  Products  >  TFAP2A (Transcription Factor AP-2-alpha, AP2-alpha, Activating Enhancer-Binding Protein 2 alpha, AP-2 Transcription Factor, Activator Protein 2, AP-2, AP2TF, TFAP2)
TFAP2A (Transcription Factor AP-2-alpha, AP2-alpha, Activating Enhancer-Binding Protein 2 alpha, AP-2 Transcription Factor, Activator Protein 2, AP-2, AP2TF, TFAP2)

TFAP2A (Transcription Factor AP-2-alpha, AP2-alpha, Activating Enhancer-Binding Protein 2 alpha, AP-2 Transcription Factor, Activator Protein 2, AP-2, AP2TF, TFAP2)

Cat no: T8195-52M1

Supplier: United States Biological
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TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle. Applications: Suitable for use in Western Blot, ELISA, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:2000 Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8195-52M1
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human TFAP2A.

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