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TFAP2A (Transcription Factor AP-2-alpha, AP2-alpha, AP-2 Transcription Factor, Activating Enhancer-binding Protein 2-alpha, Activator Protein 2, AP-2, AP2TF, TFAP2)

Cat no: T8195-52Q

TFAP2A (Transcription Factor AP-2-alpha, AP2-alpha, AP-2 Transcription Factor, Activating Enhancer-binding Protein 2-alpha, Activator Protein 2, AP-2, AP2TF, TFAP2)

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.\n\nApplications:\nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml\nImmunohistochemistry: Frozen\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T8195-52Q

Size

50ug

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG

Additional Info

Recognizes both the alpha and beta isoforms of human AP-2.

Read more on Supplier website

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Mouse

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Mouse

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Mouse

More info
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