TFIIE-beta Peptide

Cat no: BS5964P

Supplier: Bioworld Technology, Inc.

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In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequencespecific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcriptional start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Human TFIIE consists of two subunits of 56 kDa and 34 kDa molecular weight, respectively. The structure of TFIIE appears to be a heterotetramer(alpha2 beta2) both subunits being required for optimal basal-level transcription .

Catalogue number:	BS5964P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P29084
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TFIIE-beta. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Transcription initiation factor IIE subunit beta; TFIIE-beta; General transcription factor IIE subunit 2; GTF2E2; TF2E2; TFIIE beta; TFIIEbeta;
Additional info:	This peptide can be used with studies using BS5964 TFIIE-beta pAb.

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TFIIE-beta Peptide

Cat no: BS5964P

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