TGF-beta 1 Antibody

Cat no: 250876

Supplier: ABBIOTEC

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Description
Additional Information

The TGF-beta superfamily is composed of numerous growth differentiation factors, including transforming growth factor beta 1, 2 , and 3 (TGF-beta 1, TGF-beta 2 and, TGF-beta 3). TGF-beta 1 controls proliferation, differentiation and other functions in many cell types. TGF-beta 1 is a potent stimulator of osteoblastic bone formation, causing chemota, Xenopus/Amphibian,is,Porcineroliferation and differentiation in committed osteoblasts. The inactive form consists of a TGF-beta 1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The active form is a disulfide-linked homodimer of mature TGF-beta 1. Defects in TGF-beta 1 are the cause of Camurati-Emgelmann disease, a progressive diaphyseal dysplasia characterized by hyperostosis ans sclerosis of the diaphyses of long bones.

Catalogue number:	250876
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P01137
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGF-beta 1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Transforming growth factor beta-1; TGF-beta-1; TGFB1; TGFB; Latency-associated peptide; LAP