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TGF-beta 1 Antibody

TGF-beta 1 Antibody

Cat no: 252152

Supplier: ABBIOTEC
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Transforming growth factor beta-1 (TGF-beta 1) is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. The inactive form consists of a TGF-beta 1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The active form is a homodimer of mature, disulfide-linked TGF-beta 1. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemota, Xenopus/Amphibian,is,Porcineroliferation and differentiation in committed osteoblasts. Defects in TGF-beta 1 are the cause of Camurati-Engelmann disease (CE), also known as progressive diaphyseal dysplasia 1 (DPD1). CE is an autosomal dominant disorder characterized by hyperostosis and sclerosis of the diaphyses of long bones. The disease typically presents in early childhood with pain,Mouse,uscular weakness and waddling gait, and in some cases other features such as e, Xenopus/Amphibian,ophthalmos, facial paralysis, hearing difficulties and loss of vision.
Catalogue number: 252152
Reactivities: Human, Mouse, Rabbit
Applications: Western Blot
Size: 0.1 mg
Accession: P01137
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human TGF-beta 1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Transforming growth factor beta-1; TGF-beta-1; TGFB1; TGFB; Latency-associated peptide; LAP
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