TGF-beta Receptor Type I Antibody

Cat no: 250879

Supplier: ABBIOTEC

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Description
Additional Information

TGF-beta receptor type I (TGFR1) forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors that autophosphorylate and activate SMAD transcriptional regulators. Although TGFR1 is ubiquitously e, Xenopus/Amphibian,pressed, it is found most abundant in placenta and least abundant in brain and heart. Defects in TGFBR1 are the cause of Loeys-Dietz syndrome type 1 and 2 (aortic aneurysm syndromes).

Catalogue number:	250879
Reactivities:	Human, Mouse
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P36897
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGFR1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	TGF-beta receptor type-1; Transforming growth factor-beta receptor type I; TGF-beta receptor type I; TGF-beta type I receptor; TbetaR-I; TGFR-1; Serine/threonine-protein kinase receptor R4; SKR4; Activin receptor-like kinase 5; ALK5; TGFBR1