TGF-beta Receptor Type II Antibody

Cat no: 250880

Supplier: ABBIOTEC

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Description
Additional Information

TGF-beta receptor type II (TGFR2) forms a heteromeric comple, Xenopus/Amphibian, with TGFR1 after binding TGF-beta at the cell surface and activates TGFR2 by phosphorylation, subsequently binding and activation of the SMAD transcriptional regulators. Defects in TGFR2 are a cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6), esophageal cancer, and Loeys-Dietz syndromes (aortic aneurism syndrome).

Catalogue number:	250880
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P37173
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGFR2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TGF-beta type II receptor; TbetaR-II; TGFR-2; TGFBR2