TGF beta1 (4F9C) Antibody

Cat no: 252657

Supplier: ABBIOTEC

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Description
Additional Information

TGF-beta 1 (Transforming growth factor beta-1) is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. The inactive form consists of a TGF-beta 1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The active form is a homodimer of mature, disulfide-linked TGF-beta 1. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemota, Xenopus/Amphibian,is,Porcineroliferation and differentiation in committed osteoblasts. Defects in TGF-beta 1 are the cause of Camurati-Engelmann disease (CE), also known as progressive diaphyseal dysplasia 1 (DPD1). CE is an autosomal dominant disorder characterized by hyperostosis and sclerosis of the diaphyses of long bones. The disease typically presents in early childhood with pain,Mouse,uscular weakness and waddling gait, and in some cases other features such as e, Xenopus/Amphibian,ophthalmos, facial paralysis, hearing difficulties and loss of vision.

Catalogue number:	252657
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P01137
Antigen:	Purified recombinant fragment of TGFbeta1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2a
Clonality:	4F9C10,1B11B7
Additional info:	Transforming growth factor beta-1; TGF-beta-1; TGFB1; TGFB; Latency-associated peptide; LAP