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TGF beta3 (G292) Peptide

Cat no: BS1363P

TGF beta3 (G292) Peptide

Transforming growth factor betas (TGFbetas) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGFbetas mediate many cell-cell interactions that occur during embryonic develop ment. Three TGFbetas have been identified in mam mals. TGFbeta1, TGFbeta2 and TGFbeta3 are each syn thesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the mol ecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approx imately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.

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SPECIFICATIONS

Catalog Number

BS1363P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TGF beta3 (G292). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P10600

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1363 TGF beta3 (G292) pAb.

Alternative Names

Transforming growth factor beta-3; TGF-beta-3; Latency-associated peptide; LAP; TGFB3; TGFbeta3; TGF beta3

SUPPLIER INFO

Bioworld Technology, Inc.

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