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TGFalpha (R139) Peptide

TGFalpha (R139) Peptide

Cat no: BS1359P

Supplier: Bioworld Technology, Inc.
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Transforming growth factor alpha (TGFalpha) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFalpha is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFalpha binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor beta. TGFalpha is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFalpha bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.
Catalogue number: BS1359P
Applications: Block/Neutralize/Inhibit
Swiss prot: P01135
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TGFalpha (R139). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Protransforming growth factor alpha; Transforming growth factor alpha; TGF-alpha; EGF-like TGF; ETGF; TGF type 1; TGFA; TGF alpha
Additional info: This peptide can be used with studies using BS1359 TGFalpha (R139) pAb.

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