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TGFbeta2 (L388) Peptide

TGFbeta2 (L388) Peptide

Cat no: BS1362P


Supplier: Bioworld Technology, Inc.
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Transforming growth factor betas (TGFbetas) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGFbetas mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.
Catalogue number: BS1362P
Applications: Block/Neutralize/Inhibit
Swiss prot: P61812
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TGFbeta2 (L388). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TGFB2; CETERMIN; G-TSF; MGC116892; POLYERGIN; TGF-BETA-2; TGF-BETA2
Additional info: This peptide can be used with studies using BS1362 TGFbeta2 (L388) pAb.

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